| Children, adolescents, nursing mothers, and women who are pregnant should avoid delta4- and
delta5-androstenediol supplements. In general, women should exercise caution in the use of
delta4- and delta5-androstenediol supplements due to possible virilizing effects. There is
no information available on the long-term safety of supplemental 4delta- or
5delta-androstenediol. Adverse effects of exogenous testosterone in men include acne,
behavioral changes, gynecomastia, testicular atrophy, and possibly an increased risk of
prostate cancer. Adverse effects of exogenous testosterone in women include acne,
amenorrhea, clitoral hypertrophy, coarsening of the skin, deepening of the voice, hirsutism,
and male-pattern baldness. In adolescents, exogenous testosterone may lead to early closing
of bone growth plates and decreased adult height. Other adverse effects of testosterone
include hepatic failure and increased platelet aggregation. This website is intended to
educate and inform, and should not replace discussions with your doctor. |