| Sesquiterpenoid lactones in Arnica, such as helenalin, are extremely poisonous and
cardiotoxic. Oral use of Arnica is considered unsafe, as is topical use of Arnica on broken
skin and open wounds. Individuals with cardiac arrythmias, hypertension, and those taking
medicines known to cause a prolonged QT interval or medicines known to be potentially
cardiotoxic, should be very careful about the use of Arnica. Ingested Arnica might cause
abdominal pain, diarrhea, nausea, vomiting, coma, and death. Individuals allergic or
hypersensitive to Arnica or to other members of the daisy family can develop anaphylaxis,
asthmatic attacks, bronchospasm, conjunctivitis, rhinitis, and urticaria. Topical Arnica may
cause contact dermatitis manifested as pruritis and erythema. Arnica may potentiate the
adverse effects of drugs known to cause a prolonged QT interval. Such drugs include
amiodarone, amitryptyline, chlorpromazine, desipramine, disopyramide, doxepim, haloperidol,
pentamidine, procainamide, prochlorperazine, quinidine, and sotalol. Arnica might potentiate
the cardiotoxicity of such medicines as doxorubicin. This website is intended to educate and
inform, and should not replace discussions with your doctor. |