| Borage Oil appears to be effective in some cases of rheumatoid arthritis. Borage Oil might
also be indicated in other inflammatory disorders, such as Sjogren's syndrome and ulcerative
colitis. Other possible indications include acute respiratory distress syndrome (ARDS),
diabetic neuropathy, elevated serum lipids, hypertension, and osteoporosis. Borage Oil has
not proved useful for menopausal flushing, premenstrual syndrome, or tardive dyskinesia. It
may be indicated in some cases for atopic dermatitis as well as for uremic skin conditions
in hemodialysis patients. Borage Oil should probably not be used in efforts to enhance
immunity, as it may be immunosuppressive. |
| Nursing mothers and women who are pregnant women should avoid using Borage Oil supplements.
Individuals with a history of partial complex seizure disorders should avoid using Borage
Oil. Individuals with other types of seizure disorders and schizophrenics who are being
treated with certain neuroleptic drugs, such as aliphatic phenothiazines, which may lower
seizure threshold, should avoid Borage Oil use. Those with hemophilia or other hemorrhagic
diatheses and those taking warfarin should exercise caution in the use of this supplement
due to possible antithrombotic activity. Before any surgical procedure, Borage Oil
supplementation should be stopped. Individuals with immune deficiency disorders, such as
AIDS, should exercise caution in the use of Borage Oil due to its possible inhibition of
lymphocyte function. Pyrrolizidine alkaloids (such as amabiline, lycopsamine and thesinine)
are found in various parts of the borage plant. The unsaturated pyrrolizidine alkaloids,
such as amabiline, are potentially hepatotoxic and carcinogenic. Amabiline hasn't been
detected in Borage Oil supplements down to five parts per million. However, chronic
consumption of Borage Oil containing levels of amabiline of one part per million might be
harmful. Individuals who use Borage Oil chronically should only use products that are
certified free of unsaturated pyrrolizidine alkaloids. Borage Oil might cause such
gastrointestinal symptoms as bloating, diarrhea, flatulence, nausea, and vomiting. Borage
Oil may precipitate symptoms of undiagnosed complex partial seizures and should be used, if
at all, with extreme caution in individuals with a history of seizure disorders or those
taking drugs that lower the seizure threshold, such as aliphatic phenothiazines. Use of
Borage Oil in schizophrenics who are being treated with certain neuroleptic agents that
lower seizure threshold might cause partial complex seizures and possibly other types of
seizures. Interactions might occur between Borage Oil and anticoagulants, such as warfarin,
as well as antiplatelet medicines, such as aspirin and NSAIDs. Such interactions might
enhance the effects of the anticoagulants and antiplatelet medicines. Manifestations of such
interactions, if they were to occur, include hematuria, nosebleeds, and increased
susceptibility to bruising. Borage Oil intake should be halted if these symptoms develop.
Interactions might occur if Borage Oil is used with supplements that have antithrombotic
activity, such as fish oils. This might be marked by nosebleeds and increased susceptibility
to bruising. Interactions may occur if Borage Oil is used with such herbs as garlic and
ginkgo. Such interactions may be marked by nosebleeds and easy bruising. This website is
intended to educate and inform, and should not replace discussions with your doctor. |