| Supplemental Calcium taken without food might increase the risk of kidney stones in women
and possibly men. It's advisable that supplemental Calcium be taken with food. Individuals
who form calcium-containing kidney stones are generally advised not to take supplemental
Calcium. Individuals with achlorhydria should take calcium carbonate with food. In general,
Calcium supplements are well tolerated. Using calcium carbonate might cause such
gastrointestinal reactions as bloating, constipation, flatulence, and gas. Prolonged use
of large doses of calcium carbonate may lead to the milk-alkali syndrome, nephrocalcinosis,
and renal insufficiency. Concurrent intake of a bisphosphonate and Calcium might decrease
bisphosphonate absorption. Concurrent use of H2 blockers (cimetidine, famotidine,
mizatidine, ranitidine) and calcium carbonate or calcium phosphate can lead to decreased
absorption of these calcium salts. Concurrent intake of levothyroxine and calcium carbonate
was shown to reduce levothyroxine absorption and increase serum thyrotropin levels.
Levothyroxine might adsorb to calcium carbonate in an acidic environment, which might block
its absorption. There is no evidence that other forms of calcium block levothyroxine
absorption if taken concurrently. Concurrent use of proton pump inhibitors (lansoprazole,
omeprazole, rabeprazole sodium) and calcium carbonate or calcium phosphate can cause
decreased absorption of these calcium salts. Concurrent use of a quinolone (ciprofloxacin,
gatifloxacin, levofloxacin, lomefloxacin, moxifloxacin, norfloxacin, ofloxacin,
sparfloxacin, trovafloxacin) and calcium might decrease the absorption of the quinolone.
Concurrent intake of a tetracycline (doxycycline, minocycline, tetracycline) and calcium
might decrease the absorption of the tetracycline. Tetracyclines may form nonabsorbable
complexes with Calcium. Concurrent use of these vitamin D analogues (calcitriol,
alfacalcidol) and Calcium can cause increased absorption of Calcium. Concurrent use of
inositol hexaphosphate (phytic acid) and Calcium might decrease the absorption of Calcium.
Concurrent use of iron and Calcium might inhibit the absorption of iron. Concurrent use of
fluoride, magnesium, phosphorous or zinc and calcium might lower the absorption of these
minerals. Concurrent use of these oligosaccharides (fructo-oligosaccharides, inulin) and
calcium might increase the absorption of Calcium in the colon. Concurrent intake of sodium
alginate and Calcium might lower the absorption of Calcium. Concurrent use of vitamin D and
Calcium might increase the absorption of Calcium. Calcium might be poorly absorbed from
foods rich in oxalic acid (beans, rhubarb, spinach, and sweet potatoes) or phytic acid (nuts
and grains, raw beans, seeds, soy isolates, and unleavened bread). Concurrent intake of a
Calcium supplement with foods rich in oxalic acid or phytic acid might lower the Calcium
absorption. The phytate associated with dietary fiber looks to be the major factor involved
in depressing absorption of Calcium. This website is intended to educate and inform, and
should not replace discussions with your doctor. |