Creatine

Supplemental Creatine might enhance performance in a few high-intensity, short-term physical activities, but there is mixed data and no ergogenic effect has been convincingly demonstrated outside of laboratory settings. Adequate safety data are still missing. Creatine might be useful in treating muscular dystrophy and amyotrophic lateral scleroses. It might also improve skeletal muscle function in some with congestive heart failure and gyrate atrophy of the retina.

Adolescents, children, nursing mothers, women who are pregnant, and anyone at risk for renal disorders such as diabetics should avoid Creatine supplements. Individuals using Creatine should have serum Creatinine levels monitored. Typical adverse effects are gastrointestinal and include diarrhea, indigestion, and nausea. Muscle cramping and strains are also common. Weight gain might occur from water retention. During a five day loading period, weight gains of 1.1 to 3.5 pounds have been noted. There are reports of elevated serum Creatinine, a metabolite of Creatine and a marker of kidney function, in some individuals who take Creatine and have normal renal function. This is reversible upon Creatine discontinuation. Anecdotal reports of adverse events to the FDA have included anxiety, atrial fibrillation, diarrhea, dyspnea, fatigue, migraine, myopathy, nervousness, polymyositis, rash, seizures, and vomiting. There are no known drug, herb, or nutritional supplement interactions. Caffeine appears to interfere with any beneficial effects of Creatine supplementation. This website is intended to educate and inform, and should not replace discussions with your doctor.