Genistein

Genistein might be useful in preventing and treating some cancers (principally breast and prostate cancers). Soy isoflavones, including Genistein, might be useful in some problems associated with menopause, including hot flashes and osteoporosis. High dietary intake of soy products in parts of Asia have a high correlation with reduced incidence of breast and prostate cancers. In one study, Genistein perinatally fed to rats significantly protected offspring from subsequent chemically induced mammary cancers. Researchers concluded that adequate perinatal exposure to Genistein can confer permanent protective effects against breast cancer. The researchers speculated that protective effects in humans, with respect to breast cancer, might depend upon exposure to Genistein early in life. More research is needed in order to clarify this issue. There are a number of studies which have shown that Genistein can inhibit prostate cancer-cell growth in vitro. Genistein might be both chemopreventive and therapeutic in prostate cancers regardless of androgen responsiveness but clinical trials are needed.

Nursing mothers and women who are pregnant should avoid the use of Genistein/Genistin supplements pending long-term safety studies. Men with prostate cancer should discuss the advisability of the use of Genistein/Genistin supplements with their doctors before deciding to use them. Women with estrogen receptor-positive tumors should apply caution in the use of Genistein/Genistin supplements and should only use them if recommended and monitored by a doctor. Genistein/Genistin intake has been linked with hypothyroidism in some people. This website is intended to educate and inform, and should not replace discussions with your doctor.